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Acomplia diet pills work on the Endocannabinoid system which
controls appetite and energy expenditure (as well as the urge
to smoke). This wonder pill selectively blocks some receptors
in the Endocannabinoid system thus creating a better balance
which in turn suppresses appetite and the longing to overeat.
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More about Acomplia
(Rimonabant):
Name Brand: Acomplia
Name Generic: Rimonabant
Name Extended:
Generic Acomplia (Rimonabant)
Pack: 20mg 120
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Category: Weight
Loss
Description: Diet
pill Acomplia (Rimonabant) is a miraculous multifunctional
pill that helps you short out obesity as well as smoking.
Acomplia diet pills work on the Endocannabinoid system which
controls appetite and energy expenditure (as well as the urge
to smoke). This wonder pill selectively blocks some receptors
in the Endocannabinoid system thus creating a better balance
which in turn suppresses appetite and the longing to overeat.
Description Extended:
Brand name: Acomplia Generic Rimonabant Generic name: Rimonabant
What is Acomplia? • Acomplia (rimonabant) is the first in
a new class of therapeutic agents called Cannabinoid-1 Receptor
Blockers (CB1). • Acomplia is used in the treatment of obesity
and related conditions. How does Acomplia work? • Acomplia
acts by selectively blocking CB1 receptors found in the brain
and in peripheral organs important in glucose and lipid (or
fat) metabolism including adipose tissue the liver gastrointestinal
tract and muscle1. • Acomplia switches off the same brain
circuits that make people hungry when they smoke cannabis.
• CB1 receptor blockade with Acomplia acts to decrease the
overactivity of the endocannabinoid system (EC system)2 3.
The EC system is a recently characterised physiological system
that includes receptors such as the CB1 receptor and it has
been shown to play an important role in regulating body weight
and in controlling energy balance as well as glucose and lipid
(or fat) metabolism. What is Acomplia used for? • Acomplia
is used complementary to diet and exercise to treat obese
or overweight patients who suffer from Type 2 diabetes and
abnormal levels of fat in the blood. • Sanofi argues that
Acomplia can also prevent the risk of cardiovascular disease.
• Patients with large waist circumference (102 cm in men and
88 cm in women) will mostly benefit from taking the drug.
Does Acomplia also aid smoking cessation? • Acomplia has been
studied by sanofi-aventis as an aid to smoking cessation based
on studies for up to one year in over 6 500 smokers motivated
to quit smoking. • Sanofi-aventis submitted a New Drug Application
to the FDA which in turn issued a non approvable letter for
Acomplia for use in smoking cessation. An approvable letter
was however issued for Acomplia for use in weight management.
Acomplia has just been approved in the European Union. Is
Acomplia approved in the United States? • No. Sanofi is still
awaiting U.S. marketing go-ahead which it has said could come
by the end of this year. • U.S. health authorities have asked
Sanofi for more information on Acomplia. • Acomplia received
European Union marketing approval in June 2006. • The first
launch will take place in Britain in July and be followed
by launches in Denmark Ireland Germany Finland and Norway
in the second half of this year according to Sanofi. What
were the results of Acomplia Clinical trial studies? • In
clinical studies Acomplia has been shown to improve a wide
array of cardiometabolic risk factors as well as promoting
sustained weight loss4 5. • Approximately half of the observed
improvement in HDL-cholesterol triglycerides and HbA1C (an
indicator of blood sugar control) in patients who received
Acomplia 20mg was beyond that expected from weight loss alone6.
What are the side-effects of Acomplia? • Side effects in the
trial on Acomplia in obesity were vomiting and nausea forcing
about 19 percent of patients to leave the trial versus 13
percent of those who took placebo. Appetite suppressant Anti
obesity drug. Acomplia is used complementary to diet and exercise
to treat .obese or overweight patients who suffer from Type
2 diabetes and abnormal levels of fat in the bloodA single
pill has been found to stop both food and cigarette cravings
enough to help people quit smoking and lose weight and could
also help curb other unhealthy urges. In one study the medicine
helped people who were overweight drop an average of 20 pounds
and in another doubled the chances that smokers would quit.
Acomplia contains the active ingredient Rimonabant. It is
a selective CB1 Endocannabinoid Receptor Antagonist.Acomplia
works by blocking receptors of a substance called cannabinoid
1 which stimulates hunger and other cravings in the brain
and is also present in fat tissue. Sanofi argues that Acomplia
can also prevent the risk ofCardiovascular disease.Patients
with large waist circumference (102 cm in men and 88 cm in
women) will mostly benefit from taking the drug.ACOMPLIA«
(rimonabant) approved as an adjunct to diet and exercise for
the treatment of obese patients (BMI ≥ 30 kg/m2) or
overweight patients (BMI > 27 kg/m2) with associated risk
factors such as type 2 diabetes or dyslipidemia.Side Effects:Acomplia
was said to be well tolerated in early tests. The only relatively
common side effects were mild GI side effects and dizziness
and these were said to be transient.
Synonyms: Slimona
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