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Acomplia (Rimonabant)

Diet pill Acomplia (Rimonabant) is a miraculous multifunctional pill that helps you short out obesity as well as smoking. Acomplia diet pills work on the Endocannabinoid system which controls appetite and energy expenditure (as well as the urge to smoke). This wonder pill selectively blocks some receptors in the Endocannabinoid system thus creating a better balance which in turn suppresses appetite and the longing to overeat.

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Name Brand: Acomplia

Name Generic: Rimonabant

Name Extended: Generic Acomplia (Rimonabant)

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Category: Weight Loss

Description: Diet pill Acomplia (Rimonabant) is a miraculous multifunctional pill that helps you short out obesity as well as smoking. Acomplia diet pills work on the Endocannabinoid system which controls appetite and energy expenditure (as well as the urge to smoke). This wonder pill selectively blocks some receptors in the Endocannabinoid system thus creating a better balance which in turn suppresses appetite and the longing to overeat.

Description Extended: Brand name: Acomplia Generic Rimonabant Generic name: Rimonabant What is Acomplia? • Acomplia (rimonabant) is the first in a new class of therapeutic agents called Cannabinoid-1 Receptor Blockers (CB1). • Acomplia is used in the treatment of obesity and related conditions. How does Acomplia work? • Acomplia acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism including adipose tissue the liver gastrointestinal tract and muscle1. • Acomplia switches off the same brain circuits that make people hungry when they smoke cannabis. • CB1 receptor blockade with Acomplia acts to decrease the overactivity of the endocannabinoid system (EC system)2 3. The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance as well as glucose and lipid (or fat) metabolism. What is Acomplia used for? • Acomplia is used complementary to diet and exercise to treat obese or overweight patients who suffer from Type 2 diabetes and abnormal levels of fat in the blood. • Sanofi argues that Acomplia can also prevent the risk of cardiovascular disease. • Patients with large waist circumference (102 cm in men and 88 cm in women) will mostly benefit from taking the drug. Does Acomplia also aid smoking cessation? • Acomplia has been studied by sanofi-aventis as an aid to smoking cessation based on studies for up to one year in over 6 500 smokers motivated to quit smoking. • Sanofi-aventis submitted a New Drug Application to the FDA which in turn issued a non approvable letter for Acomplia for use in smoking cessation. An approvable letter was however issued for Acomplia for use in weight management. Acomplia has just been approved in the European Union. Is Acomplia approved in the United States? • No. Sanofi is still awaiting U.S. marketing go-ahead which it has said could come by the end of this year. • U.S. health authorities have asked Sanofi for more information on Acomplia. • Acomplia received European Union marketing approval in June 2006. • The first launch will take place in Britain in July and be followed by launches in Denmark Ireland Germany Finland and Norway in the second half of this year according to Sanofi. What were the results of Acomplia Clinical trial studies? • In clinical studies Acomplia has been shown to improve a wide array of cardiometabolic risk factors as well as promoting sustained weight loss4 5. • Approximately half of the observed improvement in HDL-cholesterol triglycerides and HbA1C (an indicator of blood sugar control) in patients who received Acomplia 20mg was beyond that expected from weight loss alone6. What are the side-effects of Acomplia? • Side effects in the trial on Acomplia in obesity were vomiting and nausea forcing about 19 percent of patients to leave the trial versus 13 percent of those who took placebo. Appetite suppressant Anti obesity drug. Acomplia is used complementary to diet and exercise to treat .obese or overweight patients who suffer from Type 2 diabetes and abnormal levels of fat in the bloodA single pill has been found to stop both food and cigarette cravings enough to help people quit smoking and lose weight and could also help curb other unhealthy urges. In one study the medicine helped people who were overweight drop an average of 20 pounds and in another doubled the chances that smokers would quit. Acomplia contains the active ingredient Rimonabant. It is a selective CB1 Endocannabinoid Receptor Antagonist.Acomplia works by blocking receptors of a substance called cannabinoid 1 which stimulates hunger and other cravings in the brain and is also present in fat tissue. Sanofi argues that Acomplia can also prevent the risk ofCardiovascular disease.Patients with large waist circumference (102 cm in men and 88 cm in women) will mostly benefit from taking the drug.ACOMPLIA« (rimonabant) approved as an adjunct to diet and exercise for the treatment of obese patients (BMI ≥ 30 kg/m2) or overweight patients (BMI > 27 kg/m2) with associated risk factors such as type 2 diabetes or dyslipidemia.Side Effects:Acomplia was said to be well tolerated in early tests. The only relatively common side effects were mild GI side effects and dizziness and these were said to be transient.

Synonyms: Slimona

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